* Ferritin's Role: Ferritin is a protein that stores iron in your body. Iron is crucial for many bodily functions, including the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which are essential for mood regulation.
* Low Ferritin and Depression: Several studies have found that individuals with depression often have significantly lower ferritin levels compared to healthy individuals. This association can exist even before the onset of iron-deficiency anemia (a more severe condition where red blood cell counts are also low).
* Mechanism: Iron deficiency can affect the brain by impairing the synthesis of these vital neurotransmitters and by causing low oxygen levels (hypoxia), which can lead to mood disturbances and cognitive changes.